We’re introducing SynthID Bio, bringing our watermarking technology to synthetic biology.
Today, we’re introducing SynthID Bio, a new technology that watermarks AI-designed proteins while preserving their biological function.
SynthID Bio embeds an imperceptible, verifiable watermark directly into biological designs, such as AI-generated protein sequences and predicted 3D structures.
In laboratory tests across target proteins, our watermarked designs successfully matched the performance and natural diversity of unwatermarked versions. This creates a vital provenance layer to strengthen biosecurity and preserve the integrity of open scientific databases.
You can read the full blog post and research on the Google DeepMind website.
Visualization of the predicted structure of our watermarked VEGF-A protein binder with watermark signal indicated by color for each amino acid.
Binding affinity, measured as KD, comparing non-watermarked and watermarked protein designs across three targets. Lower indicates stronger binders.
On 7PPA, we show the AF3 predicted structure (left), the ground truth structure (middle), and the watermarked structure (right).
